Descriptive Study of Malabsorption Syndrome at the Postgraduate Hospital in Khost, Afghanistan

Mohammad Anwar Trezai; Sultan Mohammad Khwaja; Said Shah Ahmadi; Shahmehmood Ranzormal

doi:10.55544/jrasb.2.5.2

Authors

Mohammad Anwar Trezai Assistant Clinical Professor and Head of Internal Medicine Department, Khost Post Graduate Hospital, AFGHANISTAN.
Sultan Mohammad Khwaja Lecture, Faculty of Medical, Shiakh Zayed University, AFGHANISTAN.
Said Shah Ahmadi Faculty of Medical, Shiakh Zayed University, AFGHANISTAN.
Shahmehmood Ranzormal Lecture, Faculty of Medical, Shiakh Zayed University, AFGHANISTAN.

DOI:

https://doi.org/10.55544/jrasb.2.5.2

Keywords:

Malabsorption syndrome, age, gender, complication, symptoms, celiac disease, accommodation

Abstract

Background: Malabsorption syndrome is a gastrointestinal condition hindering the efficient absorption of nutrients from food. Multiple factors contribute, primarily linked to mucosal damage within the small intestine, the primary site for nutrient absorption. (1)

Research Goal: The Frequency and pattern of Malabsorption in khost provincial and specialized Hospital During year1400 hijri shamsi.

Research rational: There is no medical information about the case in the civil and specialized hospital of khost, also the disease events constitute a large percentage of disease events if diagnosed and treat in time the complication rate will be reduced.

Methodology: Our study is a descriptive case series conducted in the year 1400. Among the 2,311 patients admitted to Khost Hospital during that time, 80 individuals were diagnosed with Malabsorption Syndrome.

Result: During the year 1400 ,2311 patients were hospitalized in khost hospital, among these, 30 patients were diagnosed as Malabsorption, most were younger than 20 and more than 60 years, most of them were female, the significant symptoms were chronic diarrhea, weight loss, dyspepsia and dehydration. most admitted patients were referred from center of khost city and major complications were weight loss, malnutrition, and anemia.

Final result: the incidence of malabsorption contains 1.29% of all other diseases, the incidence is higher in patients who aged less than 20 and more than 60 years, the incidence is higher in female than male, the events are more in the central areas of the khost than the districts., the common symptoms are chronic diarrhea, weight loss, dyspepsia. The weight loss, malnutrition, and anemia were the major complications.

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References

https://my.clevelandclinic.org/health/diseases/22722malabsorption.

Tyesha Zuvarox; Chris Belletieri Malabsorption Syndromes. Lower Bucks Hospital July 25, 2022

Gloria Galli,* Giulia Amici, Laura Conti, Edith Lahner, Bruno Annibale, and Marilia CarabottiSex–Gender Differences in Adult Coeliac Disease at Diagnosis and Gluten-Free-Diet Follow-Up PMID: 35956368

Omar I Saadah 1, Sharifa A Alghamdi 2, Haifa H Sindi 3, Huda Alhunaitti 4, Yagoub Y Bin-Taleb 5, Bakr H Alhussaini 6Congenital glucose-galactose malabsorption: a descriptive study of clinical characteristics and outcome from Western SaudiArabiaPMID: 24630509

Uday C. Ghoshal, Mansi Mehrotra, Sunil Kumar, Ujjala Ghoshal,* Narendra Krishnani,** Asha Misra, Rakesh Aggarwal, and Gourdas ChoudhuriSpectrum of malabsorption syndrome among adults & factors differentiating celiac disease & tropical malabsorptionPMID: 23041739

McQuaid Kenneth R. Gastrointestinal Disorders,In: PapadakisMoxine A, Mephee Stephen J. Current Medical Diagnosis and Treatment.McGraw- Hill Companies Inc.2022, 61 edition:PP (1621-1636)

Davidson’s principles and practice of Medicine. ChurchillLivingstone Publications, 201, 23edition: PP ( 783 – 789 )

LaineLoren;, Harrison’s Internal Medicine,McGraw- Hill Companies Inc (2021,21th) edition, Volume I, PP (2458 - 2469).

McQuaid Kenneth R. Gastrointestinal Disorders,In: PapadakisMoxine A, Mephee Stephen J. Current Medical Diagnosis and Treatment.McGraw- Hill Companies Inc.2022, 61 edition:PP (241-256)

Guyton Arthur C, Hall John E. Text book of Medical Physiology,Saunders publications 2015; 13 th edition.

Foster Corey, Mistry Neville F. et al. The WashingtonManual of Medical Therapeutis. 2010, 36th edition.

Davidson’s principles and practice of Medicine. ChurchillLivingstone Publications, 201, 23edition.

_ZuvaroxT,BelletieriC. MalabsorptionSyndromes. (https://www.ncbi.nlm.nih.gov/books/NBK553106/) [Updated 2021 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-

Biagi F., Luinetti O., Campanella J., et al. Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? J. Clin. Pathol. 2004;57:835–839

Owens S.R., Greenson J.K. The pathology of malabsorption: current concepts. Histopathology. 2007;50:64–82.

Serra S., Jani P.A. An approach to duodenal biopsies. J. Clin. Pathol. 2006;59:1133–1150

Walker M.M., Talley N.J. Clinical value of duodenal biopsies – beyond the diagnosis of coeliac disease. Pathol. Res. Pract. 2011;207:538–544.

Alsaigh N., Odze R., Goldman H., Antonioli D., Ott M.J., Leichtner A. Gastric and oesophageal intraepithelial lymphocytes in paediatric coeliac disease. Am. J. Surg. Pathol. 1996;20:865–870.

Brown I., Mino-Kenudson M., Deshpande V., Lauwers G.Y. Intraepithelial lymphocytosis in architecturally preserved proximal small intestinal mucosa. Arch. Pathol. Lab. Med. 2006;130:1020–1025.

Ravelli A., Bolognini S., Gambarotti M., Villanaci V. Variability of histologic lesions in relation to biopsy site in gluten sensitive enteropathy. Am. J. Gastroenterol. 2005;100:177–185.