Article Review: The Approach to Celiac Disease in Children

Mohannad Kadhim Mohammed Ali

doi:10.55544/jrasb.1.4.5

Authors

Mohannad Kadhim Mohammed Ali Senior Consultant Paediatrician, Faculty of Medicine, Wasit University, IRAQ.

DOI:

https://doi.org/10.55544/jrasb.1.4.5

Keywords:

Celiac Disease, Gluten, Epidemiology, Pathogenesis

Abstract

A persistent, global, immunological illness called CD affects those who are genetically predisposed to it. Inside the average population, celiac disease is thought to affect 1% of people worldwide. Its incidence varies according to regional or racial differences. Due to improved medical understanding with awareness, as well as the widespread use of extremely sensitive or precise diagnostic tests for celiac disease, the incidence of celiac disease had considerably grown over the last thirty years. Even though there is more understanding or awareness regarding celiac disease, up to 95% of celiac sufferers still go untreated. The uneven nature of small intestinal mucosa alterations may result in false-negative small intestinal histopathology. Throughout Western Europe, one percent of people suffer with CD.

The research of milder clinical traits or the use of serological testing has boosted the detection accuracy. Although the age of presentation varies, individuals often present during the fourth or sixth decades. Compared to juvenile instances, adult’s instances of CD are more prevalent, with individuals as old as 65 are now being identified or given diagnoses. It usually happens after adding gluten to the diet. There is a considerable change toward fewer patients presenting with mild dementia or as symptomatic adults identified during testing, however there is a tendency towards decreasing individuals who present with severe CD marked by diarrhoea.

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