A Review on Vitamin D Deficiency

Priya Shukla; Mamta Kumari; Mayankesh Pandey

doi:10.55544/jrasb.2.2.10

Authors

Priya Shukla Department of Pharmacy Maharana Pratap College of Pharmacy, Kanpur Uttar Pradesh, INDIA.
Mamta Kumari Department of Pharmacy Maharana Pratap College of Pharmacy, Kanpur Uttar Pradesh, INDIA.
Mayankesh Pandey Department of Pharmacy, Vidya Bhavan College of Pharmacy, Uttar Pradesh, INDIA.

DOI:

https://doi.org/10.55544/jrasb.2.2.10

Keywords:

Vitamin D, bone metabolism, skeletal disease, immune-modulating, autoimmune

Abstract

Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism and seems to have some anti-inflammatory and immune-modulating properties. In addition, recent epidemiologic studies have observed relationships between low vitamin D levels and multiple disease states. Low vitamin D levels are associated with increased overall and cardiovascular mortality, cancer incidence and mortality, and autoimmune diseases such as multiple sclerosis. Although it is well known that the combination of vitamin D and calcium is necessary to maintain bone density as people age, vitamin D may also be an independent risk factor for falls among the elderly.

Vitamin D had been linked to skeletal disease including calcium, phosphorus, and bone metabolism, osteoporosis, fractures, muscle strength, and falls. In the 2000s, growing scientific attention turned to non-skeletal chronic diseases as vitamin D deficiency was linked to cancer, cardiovascular diseases, metabolic disorders, infectious diseases, and autoimmune diseases, as well as mortality.

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Anubhav Dubey, Niladry Sekhar Ghosh, Anubha Gupta, Shweta Singh, 2023. A review on current epidemiology and molecular studies of lumpy skin disease virus-an emerging worldwide threat to domestic animals. Journal of medical pharmaceutical and allied sciences, V 12 - I 1, Pages - 5635 – 5643.DOI: 10.55522/jmpas.V12I1.4583.

Pate S, Dubey A, Gupta Ak, Ghosh NS, (2023). Evaluation of Antimicrobial Activity of Calotropis Gigantea Extracts on Two Main Skin Infection Causing Bacteria - Escherichia Coli and Staphylococcus Aureus.12(1):145-157.

Dubey A, Ghosh NS, Singh R. Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science. J Pharm Negative Results 2022;13(3): 1-7.DOI:10.47750/pnr.2022.13.03.001.

Anubhav Dubey, Raghuvendra Singh, Ashish Kumar, Gaurav Mishra, Anubha Gupta, Anuj Sonker, & Amit Mishra. (2022). A Critical Review on Changing Epidemiology of Human Monkeypox-A Current Threat with Multi-Country Outbreak. Journal of Pharmaceutical Negative Results, 660–671. Retrieved from https://www.pnrjournal.com/index.php/home/article/view/738.

Dubey, A., Yadav, P., Peeyush, , Verma, P., & Kumar, R. (2022). Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line. Journal of Drug Delivery and Therapeutics, 12(1), 51-55. https://doi.org/10.22270/jddt.v12i1.5172

Dubey A, Dash SL, Kumari P, Patel S, Singh S, Agarwal S, A Comprehensive Review on Recent Progress in Invivo and Invitro Models for Hyperlipidemia Studies. Pakistan Heart Journal, 2023:56(01),286-297. http://www.pkheartjournal.com.

Anubhav Dubey, Niladry Sekhar Ghosh, Anubha Gupta, Shweta Singh, 2023. A review on current epidemiology and molecular studies of lumpy skin disease virus-an emerging worldwide threat to domestic animals. Journal of medical pharmaceutical and allied sciences, V 12 - I 1, Pages - 5635 – 5643.DOI: 10.55522/jmpas.V12I1.4583.

Pate S, Dubey A, Gupta Ak, Ghosh NS, (2023). Evaluation of Antimicrobial Activity of Calotropis Gigantea Extracts on Two Main Skin Infection Causing Bacteria - Escherichia Coli and Staphylococcus Aureus.12(1):145-157.

Dubey A, Ghosh NS, Singh R. Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science. J Pharm Negative Results 2022;13(3): 1-7. DOI: 10.47750/pnr.2022.13.03.001.

Anubhav Dubey, Raghuvendra Singh, Ashish Kumar, Gaurav Mishra, Anubha Gupta, Anuj Sonker, & Amit Mishra. (2022). A Critical Review on Changing Epidemiology of Human Monkeypox-A Current Threat with Multi-Country Outbreak. Journal of Pharmaceutical Negative Results, 660–671. Retrieved from https://www.pnrjournal.com/index.php/home/article/view/738.

Dubey, A., Yadav, P., Peeyush, Verma, P., & Kumar, R. (2022). Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line. Journal of Drug Delivery and Therapeutics, 12(1), 51-55. https://doi.org/10.22270/jddt.v12i1.5172

Dubey Anubhav Ghosh Sekhar Niladry, Saxena Gyanendra Kumar, Purohit Debashis, Singh Shweta, (2022). Management implications for neurotoxic effects associated with antibiotic use. Neuro Quantology, 6(20), 304-328. doi: 10.14704/nq.2022.20.6.NQ22034.

Dubey, A., Ghosh, N. S., Rathor, V. P. S., Patel, S., Patel, B., &Purohit, D. (2022). Sars- COV-2 infection leads to neurodegenerative or neuropsychiatric diseases. International Journal of Health Sciences, 6(S3), 2184–2197. https://doi.org/10.53730/ijhs.v6nS3.5980.

Yadav, K., Sachan, A., Kumar, S., & Dubey, A. (2022). Techniques For Increasing Solubility: A Review of Conventional and New Strategies. Asian Journal of Pharmaceutical Research and Development, 10(2), 144-153.

Kumar, A.., Dubey, A. ., & Singh, R. . (2022). Investigation on Anti-Ulcer Activity of Momordica dioica Fruits in Wistar Rat. International Journal for Research in Applied Sciences and Biotechnology, 9(1), 105–111. https://doi.org/10.31033/ijrasb.9.1.12

Dubey Anubhav, Tiwari Mamta, Kumar Vikas, Srivastava, Kshama, Singh, Akanksha. Investigation of Anti-Hyperlipidemic Activity of Vinpocetine in Wistar Rat. International Journal of Pharmaceutical Research 2020; 12(02):1879-1882. DOI: https://doi.org/10.31838/ijpr/2020.12.02.250.

Anubhav Dubey, Niladry Sekhar Ghosh, Anubha Gupta, Shweta Singh, 2023. A review on current epidemiology and molecular studies of lumpy skin disease virus-an emerging worldwide threat to domestic animals. Journal of medical pharmaceutical and allied sciences, V 12 - I 1, Pages - 5635 – 5643. DOI: 10.55522/jmpas.V12I1.4583.